LQB292 Lecture 7: Introduction to Immunology

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Lqb292 principles of infection and immunity introduction to immunology. Immune response dynamic communication network that defends the body. Recognises infectious organisms and provides/initiates protective counter-measures. Response is the same each time infection occurs to prevent entry of pathogens destroy quickly if they entry. Cells included neutrophils, macrophages, nk cells: adaptive immunity 2nd line of defence. Lymphocytes the adaptive immune system is coordinated by lymphocytes which result in antibody production. The immune system can be divided into three basic lines of defence against pathogenic infection: The first line of defence the surface barriers that prevent the entry of pathogens into the body. Secretions of skin and mucous membranes: both the skin and mucous membranes release chemical secretions restricting the growth of microbes on surfaces. If pathogens cannot enter the host body they cannot disrupt normal physiological functions and cause disease. Mucous membranes: made up of different types of epithelium (site dependent) Not effected by weak acids and bases.

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