LSB111 Lecture Notes - Lecture 6: Sepsis, Malaria, Mycobacterium Tuberculosis

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28 Aug 2018
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Le(cid:272)ture 6 i(cid:373)(cid:373)u(cid:374)e respo(cid:374)se/ mi(cid:272)ro(cid:271)es a(cid:374)d disease. Immune system functions to protect against infectious pathogens, foreign substances e. g. toxins and eliminate unwanted/ damaged e. g. Immune system functions to protect against infectious pathogens, foreign substances e. g. toxins and eliminate unwanted/ damaged e. g. tumours: 2 major divisions. Fast response: 1st line of difference, defense include: Slow response: 2nd line of defense, antigen is a molecule capable of inducing an immune response, highly specific for particular antigens, cells. Improvement in recognition of the pathogen - "memory: t lymphocytes - control or destroy foreign bodies marked by the b lymphocytes, cd4 - helper, coordinate immune response (the leader, e. g. Hiv destroys the cd4 which destroys immune response thus can get sick very quickly: activation of macrophages. Lymphoid organs/ tissue: primary lymphoid organs produce and mature lymphocytes, bone marrow, thymus, secondary lymphoid tissue/ organs are sites of adaptive immune response to antigen e. g. spleen, lymph nodes, tonsils.

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