PHYS20009 Lecture Notes - Lecture 11: Animal Ethics, Acetylcholine

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* all experimental protocols must first receive approval from a human or animal ethics committee before they can be conducted in the laboratory. * a(cid:374)y protocol i(cid:374)volvi(cid:374)g a(cid:374) a(cid:374)i(cid:373)al (cid:373)ust take the a(cid:374)i(cid:373)a s co(cid:373)fort i(cid:374)to accou(cid:374)t and minimise distress. * any protocol involving humans must not only minimize distress, but also be mindful of any long term consequence of treatments. * human participants must also be informed of any consequences, and give written consent before they participate. * need to consider appropriate invasive procedures, pain/discomfort/stress, anaesthetics, bias, number of subjects. * may be unfair to give placebo if actual drug has beneficial impacts. * a rabbit has its blood constantly at the same height as the heart. So, the changes that occur in a human are likely to be very different to that of a rabbit due to constantly changing positions. * it is not ethical to first test on a human, must first test on an animal.

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