BIOM30001 Lecture Notes - Lecture 6: Coronary Circulation, Atherosclerosis, Hormone Therapy

• School: University of Melbourne
• Department: Biomedicine
• Course: BIOM30001
• Professor: All

Document Summary

Heart attack: obstruction of coronary arteries which supply blood to muscle of heart. Loss of pumping capacity: death of coronary arteries due to hypoxia/lack of o2. Stroke: affecting the brain, blockade of blood supply in brain, haemorrhage stroke, 50% australian. Left ventricular size: reflects high bp if large, also body mass and diabetes condition, enlargement due to high peripheral resistance/bp, very important, also irreversible. In sclerosis, partial blockade of vessel (to brain or to heart) Have to reverse it to determine whether it is related to increase cvd risk. But some factors like age cannot be returned. Weight gain promotes major cvd traits (primary risk) Age is the single most important risk factor. 80% of cvd occur in >65-year-old elderly: arteries get worsen when we get older, tear/stretch of endothelium. Men die earlier and more frequently from cvd. Wo(cid:373)e(cid:374) are (cid:862)prote(cid:272)ted(cid:863) (cid:271)efore (cid:373)e(cid:374)opause: even after menopause, men has higher risk. Hormone therapy in the menopause dose not reduce cvd.