HHP 2200 Lecture Notes - Lecture 11: Peripheral Artery Disease, Coronary Artery Disease, Cerebrovascular Disease
3 May 2018
School
Department
Course
Professor
Cardiovascular Disease
• Group of disorders of the heart and blood vessels
o Coronary heart disease (heart attack)
o Cerebrovascular disease (brain – stroke)
o Peripheral vascular disease (limbs)
• Mechanisms
o Atherosclerosis – plaque buildup in arteries
o Arteriosclerosis – hardening of the arteries
Cardiovascular Disease
• Group of disorders of the heart and blood vessels
o Coronary heart disease (heart attack)
o Cerebrovascular disease (brain- stroke)
o Peripheral vascular disease (limbs)
• Mechanisms
o Atherosclerosis- plaque build up
CVD Risk Factors
• Non Modifiable
o Ages ca’t chage our age
▪ 45 years men
▪ 55 years women
o Faily History of CVD ca’t chage who our faily is
▪ < 55 years father
▪ < 65 years mother
• Modifiable
o Physical inactivity
▪ < 90 min/week
o Obesity
▪ BMI > 30
o Waist circumference (abdominal or visceral fat)
▪ Men= > 40 inches
▪ Women= > 35 inches
o Tobacco Use
▪ Damages blood vessels
▪ Increases clotting
o Elevated inflammatory biomarkers
▪ C-reactive protein
o Hypertension (high blood pressure)
o Dyslipidemia
o Diabetes
o Metabolic syndrome (grouping of multiple of these factors (out of 5 have to have 3))
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Document Summary
Cardiovascular disease: group of disorders of the heart and blood vessels, coronary heart disease (heart attack, cerebrovascular disease (brain stroke, peripheral vascular disease (limbs, mechanisms, atherosclerosis plaque buildup in arteries, arteriosclerosis hardening of the arteries. Cardiovascular disease: group of disorders of the heart and blood vessels, coronary heart disease (heart attack, cerebrovascular disease (brain- stroke, peripheral vascular disease (limbs, mechanisms, atherosclerosis- plaque build up. Increases clotting: elevated inflammatory biomarkers, c-reactive protein, hypertension (high blood pressure, dyslipidemia, diabetes, metabolic syndrome (grouping of multiple of these factors (out of 5 have to have 3)) Inactive- 30% greater risk of developing hypertension: following exercise, bp lower by 3-15 mmhg for ~10-15 hours, bp = (hr x sv) x peripheral resistance, hr x sr (cardiac output) Pa goal hypertension: goal, short (10min) or longer (30+ min) reduced bp, multiple sessions may lower bp throughout the day. Dyslipidemia: cholesterol (lipids) and fats (triglycerides) in blood.
