SLE206 Lecture Notes - Lecture 5: Inner Membrane, Endoplasmic Reticulum, Nuclear Pore
Document Summary
Intracellular compartments and protein transport- class 5 learning objectives. To appreciate the existence of different organelles within the cells. Cytosol: contains many metabolic pathways, protein synthesis and the cytoskeleton. Endoplasmic reticulum: synthesis of lipids and proteins for distribution to many organelles and plasma membrane. Golgi apparatus: modification, sorting and packaging of proteins and lipids for either secretion or delivery to another organelle. Chloroplasts: atp synthesis and carbon fixation by photosynthesis. To learn that membranes are present within cells and are associated with organelles. To appreciate the evolution of internal membranes and internal compartments. Nuclear membranes and the er evolved through invagination of the plasma membrane. Mitochondria originated from an aerobic prokaryote being engulfed by a larger anaerobic eukaryotic cell. To be familiar with different methods of protein transport within cells. Gated transport: nucleus to cytoplasm through nuclear pores which function as selective gates. Transmembrane transport: membrane bound protein translocators (eg. cytosol to er)