POPH3000 Lecture Notes - Lecture 14: Senescence, Apoptosis, Malaria

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12 Jan 2020
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The major burden of disease and effects of human life were seen due to infectious disease in the past. This is less so in the developed world. Not directly communicable lasts several years (according to who, only 3 months) degenerative pathological imbalance. Significant burden of mortality and morbidity -> 60% Delay onset = reduce period lived with disability/chronic disease. 75% medical expenditure in us to chronic disease. In australia -> 10-11% of expenditure due to heart disease alone. People are also living longer with chronic disease. Senescence apoptosis -> age related decline in organ functionality. Mcginnis & foege (1993) ten controllable factors related to premature death. Poph3000 - introduction to population helth page 1. 80% of premature deaths can be attributed to: People in low socioeconomic groups have a higher risk of dying of diabetes than people form a high socioeconomic disease. Change and health practice outside the clinical context. Focus on the maintenance of health before disease occurs.

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