L41 BIOL 4810 Chapter Notes - Chapter 13: Enzyme, Stereospecificity, Eating Animals
17 Dec 2018
School
Department
Course
Professor
Document Summary
Substrate binding site situated at cleft on enzyme that is geometrically or electronically complementary to substrate. Intermediate: preformed site that changes conformation upon binding. Active sites are asymmetric so stereospecificity is important e. g. your left glove will not fit on your right hand. Active sites are asymmetric so stereospecificity is important e. g. your left glove will not fit on your right hand e. g. a left glove that is a size too small may not fit on your left hand. Some enzymes are absolutely specific for a single substrate, while most can catalyze a range. Cofactors can be transiently associated with an enzyme. Can be prosthetic groups which are permanently associated with protein by covalent bonds. Apoenzyme: catalytically inactive protein that results from removal of the cofactor. Many organisms cannot synthesize certain portions of essential cofactors. These substances are provided in the diet (vitamins) Vitamins that are coenzymes in human diet are all water-soluble.
