NSC-2201 Chapter Notes - Chapter 3: Astrocyte, Nernst Equation, Potassium Channel
1 May 2017
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Ch 3 the neuronal membrane at rest p. 55-79. The phospholipid membrane: phospholipids are main chemical building blocks of cell membranes, have hydrophilic head and hydrophobic tail, form phospholipid bilayer with hydrophilic heads facing out and hydrophobic tails facing in. Ion pumps: use atp to transport ions against their concentration/charge gradients. Diffusion: diffusion: movement of ions from areas of high concentration to areas of low concentration, concentration gradient: difference in concentration between two areas, diffusion can only happen with, 1. Ions in membrane that are permeable to the ion: 2. Membrane must possess channels permeable to that ion (conductance: 2. The ionic basis of the resting membrane potential: membrane potential is voltage across the neuronal membrane at any time, typical resting potential is -65 mv. Equilibrium potentials: equilibrium state is reached where diffusional and electrical forces are equal and opposite, ionic equilibrium potential aka equilibrium potential: electrical potential difference that exactly balances an ionic concentration gradient, 1.
