PHYSIOL 335 Chapter Notes - Chapter 12: Abo Blood Group System, Hematopoietic Stem Cell Transplantation, Bone Marrow

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O2, co2, nutrients, wastes, heat, hormones, etc: regulation. Homeostasis, ph (buffers), body temperature, etc: protection. Slightly alkaline: plasma--more plasma than rbc (and more rbc than wbc) Water is the #1 component of plasma (know this not percentage) Proteins: albumin, globulins, fibrinogen: formed elements (cells/cell fragments) - (most are rbc) Hemocytoblasts (pluripotent stem cells: pluripotent definition: capable of giving rise to several different kids of cells. Can turn into platelets, wbc, and rbc: when you are on a bone marrow transplant list, doctors take hemocytoblasts. Erythrocytes (rbc) anatomy: shape is biconcave discs. Gives it a large surface area (surface area to volume ration is very high) good for gas exchange. Has to fold when it goes through capillary: no nuclei and no other organelles. Can"t regenerate: life span 120 days. Make 2 million new rbc every second: main function: transport gases (limited metabolic activity) Doesn"t use o2 or co2 itself: contain hemoglobin molecules (oxygen carrying protein)

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