NURS-UL 3365 Chapter Notes - Chapter 31: Thyroid, Thyroid Storm, Euthyroid
5 Mar 2020
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Tsh: endogenous substance secreted by pituitary gland controls release of thyroid hormones. Thyroxine (t4): principle thyroid hormone influences metabolic rate; larger quantities. Triiodothyroxine (t3): secondary thyroid potency 4 times greater than t4. Secondary hypothyroidism: begins at pituitary gland level resulting in decreased secretion of tsh. Early life: cretinism: low metabolic rate, retarded growth and sexual development. Myxedema: decreased metabolic rate, loss of mental and physical stamina, weight gain, hair loss, firm edema, yellow dull skin. Increased metabolism: diarrhea, flushing, increased appetite, muscle weakness, fatigue, palpitations, irritability, nervousness, sleep disorders, heat intolerance, altered menstrual flow. Cv: increased number of myocardial beta adrenergic receptors, increased cardiac output. Diuretic effect: increased renal flow and increased gfr. During pregnancy with dose adjustments every 4 weeks. Other: menses irregular, weight loss, sweating, heat intolerance, fever. Methimazole and propylthiouracil precursors of t3 and t4. Inhibit incorporation of iodine molecule to tyrosine, required to make. Propylthiouracil inhibits travel of t3 and t4 in peripheral circulation.
