HUN2201 Chapter Notes - Chapter 8: Riboflavin, Glutathione Peroxidase, Neural Tube Defect
Document Summary
Are needed for generating energy from macronutrients. Coenzyme thiamin diphosphate is required for metabolism of glucose and branched-chain amino acids. Assists in production of dna and rna and synthesis of neurotransmitters. Food sources: pork products, sunflower seeds, beans, whole or enriched grains. In(cid:448)ol(cid:448)ed in oxidation reduction reactions (cid:449)ithin the electron transport chain. Part of coenzyme required by glutathione peroxidase to fight oxidative damage (antioxidant) Food sources: milk, dairy, eggs, meat, broccoli, enriched grains and breads. Ariboflavinosis: riboflavin deficiency; sore throat, swollen mucous membranes. Required for oxidation reduction reactions of carbohydrates, proteins, and fats. Can be made in limited amounts from amino acid tryptophan. Food sources: meat, fish, poultry, enriched breads and cereals. Roles include: amino acid and carbohydrate metabolism, gluconeogenesis, neurotransmitter and heme synthesis. Immune function: metabolism of niacin, folate and carnitine, reduction in cardiovascular disease. Food sources: meat, fish (tuna), poultry, enriched cereals, starchy vegetables. Toxicity from high-dose supplements: nerve damage, skin lesions.
