BSC 2010 Chapter 12: Chapter 12 Cell Cycle

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CHAPTER 12: Mitosis
Cell divisions in Prokaryotes and Eukaryotes
A. Prokaryotes: binary fission- produces
genetically identical daughter cells
Circular DNA
B. Eukaryotes:
- mitosis- produces genetically identical daughter cells
for all body cells except gametes
-meiosis- produces genetically different daughter cells
for gametes
DNA wrapped around 8 histone proteins (nucleosome)
Cell cycle- the life of a cell from the time its first
formed (from a dividing parent cell) until its own
division into two cells
Central Dogma of Biology:
DNA (Transcription) RNA (Translation) proteins
genome- cell's collection of DNA
2/3% of chromosomal DNA accounts for genes
10% of DNA codes for proteins (90% of DNA does NOT code
for proteins)
Cell's genome must be replicated before the cell can divide
into a genetically identical daughter cell
1. Somatic Cell
Normal body cells, with exception of gametes
46 chromosomes (doploid)
Cells divide through mitosis- genetically identical
daughter cells produced
Chromrosomes consist of 2 sister chromatids (2 copies
of each chromosome) attached at centromere,
connected by kinetochore proteins
2. Gamete
Spem and egg cells
23 chromosomes (haploid)
Cells divide through meiosis-
genetically different daughter
cells produced
Chromosomes consist of one
copy of each chromosome
Two types of cells (referring to number of chromosomes present)
The Cell Cycle: (2 main phases)
A. Interphase
1. G1- Cell grows while carrying out cell
functions unique to its cell type (46
chromosomes)
2. S (DNA Synthesis)- Cell continues to carry
out normal cell functions but also duplicates
its chromosomes (46*2=92 chromosomes)
3. G2- Second period of growth and
preparation for cell divisions
B. Mitotic Phase
1. Mitosis- Cell’s nucleus duplicates, then divides
2. Cytokinesis- Cell duplicates, forming two
separate cells
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Document Summary

Cell divisions in prokaryotes and eukaryotes: prokaryotes: binary fission- produces genetically identical daughter cells. Mitosis- produces genetically identical daughter cells for all body cells except gametes for gametes. Dna wrapped around 8 histone proteins (nucleosome) Cell cycle- the life of a cell from the time its first formed (from a dividing parent cell) until its own division into two cells. Dna (transcription) rna (translation) proteins genome- cell"s collection of dna. 10% of dna codes for proteins (90% of dna does not code for proteins) Cell"s genome must be replicated before the cell can divide into a genetically identical daughter cell: somatic cell. Two types of cells (referring to number of chromosomes present) Normal body cells, with exception of gametes. Cells divide through mitosis- genetically identical daughter cells produced. Chromrosomes consist of 2 sister chromatids (2 copies of each chromosome) attached at centromere, connected by kinetochore proteins: gamete. Cells divide through meiosis- genetically different daughter cells produced.

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