BSC 2010 Chapter Notes - Chapter 18: Operon, Corepressor, Repressor
Document Summary
Prokaryotes regulate genes by: gene expression & feedback inhibition. Regulations of gene expression in prokaryotes is accomplished by the operon. Operon: a cluster of functionally related genes that can be controlled by a single on & off switch, the regulatory switch is a segment of dna called the operator, usually positioned within the. Promoter: an operon is composed of: operator, promoter, and genes. 3 components: operator: controls rna polymerase across to the genes, promoter region: where rna polymerase initially attaches to, genes: stretch of dna required for total enzyme production. Regulation of operon: regulatory genes: located away from operon. Produce repressor proteins that may bind to operator: if operator is bound to repressor protein, rna polymerase is blocked. Repressible operons (trip operon: anabolic in nature, are normally on, but can be turned off, repressor protein is normally inactive but can be activated when necessary.