KAAP309 Chapter Notes - Chapter 5: Stratum Corneum, Stratum Granulosum, Stratum Spinosum

• School: University of Delaware
• Department: Kinesiology & Appl Physiology
• Course: KAAP309
• Professor: Rose William

Document Summary

Dermcidin in sweat & bacterial substances in sebum kill bacteria. Natural antibiotics: defensins that punch holes in bacteria. Melanin: chemical pigment shield to prevent uv damage. Barrier ability rises from structure of stratum corneum: bricks and mortar. Bricks : multiple layers of dead flat cells. Mortar : glycolipids that surround the cells: block diffusion of water/water-soluble substances between cells. Substances that can penetrate skin in limited amounts: Second line of defense to foreign invaders. Body works best when temperature remains within homeostatic limits. Respond to stimuli that arise from outside the body. Sunlight modified cholesterol molecules are converted to vitamin d precursor. Precursor transported to other parts of the body vitamin d. Chemical conversions to supplement those of the liver: keratinized enzymes. Muscles need larger blood supply ns constricts blood vessels. Body eliminates limited amounts of n-containing wastes in sweat: Varies in thickness: 1. 5 4. 0 mm.