BISC208 Chapter Notes - Chapter 23: Natural Selection 2, Allele Frequency, Genotype Frequency

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Evolution a change in allele frequencies, and thus heritable traits, in a population over time is driven by four processes: natural selection, genetic drift, gene flow, mutation. Natural selection is not only the process responsible for evolution, each of the four evolutionary processes have different consequences for genetic variation and fitness. Genotype frequencies: p2 + 2pq + q2 = 1: when alleles are transmitted via meiosis and random combinations of gametes, that frequencies do not change over time. The mathematical model underlying the hardy weinberg principle is based on five important assumptions about how populations and alleles behave: random mating, no natural selection, no genetic drift (random allele frequency changes, no gene flow, no mutation. Four of these factors (natural selection, genetic drift, gene flow, mutation) are processes of evolution. If biologists observe frequencies that are not in hardy-weinberg equilibrium, it means that something interesting is going on. Hardy-weinberg principle: compare the observed and expected values.

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