BILD 2 Chapter Notes - Chapter 35: Antigen-Presenting Cell, Antigen, Clonal Selection

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Give examples of physical and chemical barrier defenses: physical: skin, mucous membranes, epithelia, cuticles, chemical: tears, saliva, secretions, compare and contrast recognition by receptors in innate and adaptive immunity. They then display the antigen from the pathogen digested : activate toll-like receptors (which recognize viruses) in innate immunity e. Basically, macrophages = antigen-presenting cell: diagram the recognition event involving an mhc molecule, a peptide epitope, and a cell surface receptor of a t cell, pathogen binds to host cell, and antigen fragments/epitope bind to mhc, and the. Some b or t cells with receptors specific for the body"s own molecules are destroyed by apoptosis. Basically, the binding of an antigen receptor to an epitope initiates cell division, and for each activated cell, the result of the proliferation is a clone. Because these cells are long-lived, they provide the basis for immunological memory.

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