NURS 3100 Chapter Notes - Chapter 2: Digoxin, Chemotherapy, Antiarrhythmic Agent
Document Summary
Rate and extent of drug absorption = important to the ability of the drug to exter its action. Factors vary with the route of administration and related to: The rate of drug dissolution (dissolving in solution) Blood flow at the site of absorption. Ph partitioning between the site of absorption and plasma. Tendency of molecules to stay on the side of the membrane where. Parenteral aka outside the gi tract (routes that go directly to the systemic they ionizing (aka ion trapping) circulation) Enteral drugs - oral routes (per os - by mouth, po) Must first pass through the liver before they reach the systemic circulation. Capsule - drugs given by mouth pass through the stomach and are metabolized in the liver before reaching systemic circulation. Syringe - drugs administered by syringe immediately enter the circulatory system. Patch - parenteral routes such as this patch release drugs directly into systemic circulation.
