ANSC 3323 Chapter Notes - Chapter 7: Cloning, Sex Selection, Dna Replication
Document Summary
Biological: embryo number & quality (age-related, mosaicism (2-5% misdiagnosis, complex disorders. Technical: labor intensive, single-cell, detection failure (false results) Economical: cost (ivf & pgd very expensive) Ethical: embryo-manipulation, sex selection for social reasons, hla-matching for cord blood, etc, carrier screening, late onset disease screening, cancer susceptibility (brca1 mutations, designer babies, disclosure of information. Safety: concern for long-term safety, is biopsy safe, does biopsy affect embryo survival, would it affect children born from this technique, for pgd< lab procedures as the same as regular ivf, isci, etc. Except 1 or 2 cells will be removed from a day 3 or day 5 embryo: amniocentesis. Sperm-sorting: pre-selection of the gender of the offspring is a subject that has held man"s attention since the beginning of recorded history. Importance of artificial sexing: economic importance, prevention of sex-linked disorders. Difficulty of artificial sexing: nature"s will to maintain sex balance, only male contributes to sex determination, little difference between x and y sperm.
