BSC 2010C Chapter Notes - Chapter 23: Allele Frequency, Mendelian Inheritance, Gene Duplication

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Important things to remember about evolution: natural selection acts on individuals. Remember individuals do not evolve but populations do (over time) Microevolution: change in allele frequencies in a population over generations. Individuals with certain inherited traits survive and reproduce better. Only natural selection causes adaptive evolution: genetic drift, gene flow: Individuals must have differences in their genes (dna sequences) for natural. Genetic variation: evolution requires variation in heritable traits selection to occur. Gene variability: measured by the average % of loci in population that are heterozygous (average heterozygosity) Nucleotide variability: measured by comparing dna sequences directly. Sources of genetic variation: new alleles can arise by mutation or gene duplication. Only mutations in gamete producing cells are passed to offspring. Many mutations are silent or neutral due to redundancy or changes only in non- coding regions. Some mutations are harmful but some may be bene cial. Population: localized group of individuals capable of interbreeding and producing fertile offspring.

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