BSC 2010C Chapter Notes - Chapter 16: Dna Polymerase Iii Holoenzyme, Dna Polymerase I, Maurice Wilkins
Document Summary
Hunt for genetic material: morgan showed that genes are located on chromosomes, scientists knew dna was a polymer of nucleotides. But chromosomes are made of both dna and proteins however so Phosphate group: dna was declared the winner by studying bacteria and the viruses tha infect them, more evidence from experiments in 1950 by edwin chargaff. But in any species: # of a = t and # of g = c: basis for these rules was not understood until the discovery of the double helix. Watson and crick (and lots of other people who helped) deduced that dna was a double helix: watson-crick model explains chargaff"s rules. Base paring rules: a paired with only t and g paired only with c . Structure of dna: double helix and base pair rules allows for mechanism of replication, shapes are like lock & key (enzyme & active site) c only ts with g and a only ts with.
