BSC 2010C Chapter Notes - Chapter 15: Y Chromosome, X-Inactivation, Wild Type

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Chromosomal theory of inheritance: beyond mendel: continued research showed the importance of chromosomes in inheritance. Mendelian genes have speci c loci (positions) on chromosomes. It is the chromosomes which undergo segregation and independent assortment: the behavior of chromosomes during meiosis can account for mendel"s laws of. Mapping genes: thomas morgan: mapped the 1st gene to a particular chromosome, worked with drosophila (fruit ies) which have 4 pairs of chromosomes. Normal red allele designated with lower case letter and + and called wild. Note: wild type is the phenotype seen most commonly in nature and can apply to many characters. Mutant allele designated with lower case letter: w. Chromosomal basis of sex: mammals (including humans): 2 types of sex chromosomes: large x and smaller y. X chromosome contains 1,110 genes: sry gene: on the y chromosome; responsible for male characteristics appear female even with a y chromosome. Mutations causing a non-functioning sry gene may cause the individual to.

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