MICROM 301 Chapter 18.1:

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10 Feb 2019
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18. 1 principles of immunization: gain of adaptive immunity through normal events like exposure to infectious. Prevent disease immediately before or after likely exposure to a pathogen. Block action of microbial toxins (c) preparation of serum (fluid portion of blood that remains after blood clots) (i) (ii) (iii) One that protects against toxin is called an antitoxin (5) there are two kinds of antisera (antitoxins) (a) hyperimmune globulin (i) (ii) (iii) Prepared from sera of donors with high amounts of antibodies to certain disease agents. Examples are (a) tetanus immune globulin (b) rabies immune globulin (c) hepatitis b immune globulin (b) immune globulin (i) (ii) (iii) Igg fraction of blood plasma pooled from many donors. Has variety of antibodies due to typical infections and vaccines experienced by the donors. Used to protect unvaccinated people who have been recently exposed to certain diseases (a) like hepatitis a (b) measles (iv)

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