CH 101 Chapter Notes - Chapter 6: Opioid Receptor, Ionic Bonding, Covalent Bond

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Provides relief from an otherwise tortuous existence: natural product derived from the sap of the opium poppy, acts by binding receptors that exist within nerve cells. When morphine binds to an opioid receptor, the transmission of nerve signals is altered, resulting in less pain, sedation, and feelings of euphoria and tranquility. Binds to opioid receptors because it fits into a special pocket (the active site) on the opioid receptor protein that normally binds endorphins. Certain parts of the molecule have a similar enough shape to endorphins that they fit the lock: morphine is a molecular imposter, mimicking the action of endorphins because of similarities in shape. Polar covalent bond- intermediate in nature between a pure covalent bond and an ionic bond: has a positive pole and a negative pole. Electronegativity- the ability of an atom to attract electrons to itself in a chemical bond: quantified by american chemist, linus pauling.

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