BSC 116 Chapter Notes - Chapter 43: Monoclonal Antibody, Lymphoblast, Immunity (Medical)

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Section 43. 1: in innate immunity, recognition and response rely on traits common to groups of pathogens: pathogen- a bacterium, fungus, virus, or other disease-causing agent. Innate immunity is found in all animals (as well as plants) Insects rely on their exoskeleton as a first line of defense against most pathogens: composed largely of chitin, chitin also lines the insect intestine, where it blocks infection by many pathogens ingested with food. Innate immune responses are distinct for different classes of pathogens. Saliva, tears, and mucous secretions that bathe various exposed epithelia provide a washing action that also inhibits colonization by fungi and bacteria. Interferons- proteins that provide innate defense by interfering with viral infections: virus-infected body cells secrete interferons, which induce nearby uninfected cells to produce substances that inhibit viral replication. Some bacteria, after being engulfed by a host cell, resist breakdown with lysosomes: make certain fungi and bacteria substantial pathogenic threats.

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