NSCI 2121 Chapter Notes - Chapter 4: Neuroectoderm, Gap Gene, Morphogen
26 Sep 2017
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Neuroectoderm- the neurogenic region of the ectoderm which develops into the nervous system. Regionalization of the neuroectoderm- division of the neuroectoderm that lays the basis for regional specialization in the structure of the mature nervous system. Neurogenesis- the formation of neural cells within the neuroectoderm. Positional information- information about the location of cells within the neural epithelium that is long-range signalled. Signaling source is also called the organizer. A signal that provokes more than one cellular response in a concentration dependent manner is called a morphogen. Neuroectoderm begins as a simple two dimensional sheet of cells. In some organisms the body is divided into segments along the. Divided into reiterated series of domains (segments); then a common local blueprint of neural cell arrangements is patterned within each segment. Bicoid gene is a major morphogen in drosophila. The first task of bicoid is to induce the synthesis of another transcription factor, hunchback, which also forms an ap concentration gradient.
