BIOL 4376 Chapter Notes - Chapter 6: Febrile Neutropenia, Avibactam, Klebsiella Pneumoniae
22 Jun 2020
School
Department
Course
Professor
Document Summary
4th gen, eliminated renally, useful spectrum (broad): mssa, strep, gnr including. Pseudomonas: main uses: hap, nosocomial infections, febrile neutropenia. Anti-mrsa cephalosporin: ceftaroline (iv only, not active against pseudomonas (very rare to be used against both, susceptible to beta-lactamases, indicated uses: sssis, cap. C e p h s (3 r d g e n ) C e fe p im e (4 t h g e n c e p h ) C e p h (c e fta ro lin e ) Monobactam: aztreonam; iv only, only active against gnr, including pseudomonas, renally eliminated, not cross-reactive w other beta-lactam allergies, except ceftazidime, main use: gram-neg infections in patients w allergies to other beta- lactams. Carbapenem+beta-lactamase inhibitor combination: agent: meropenem+vaborbactam, spectrum: as meropenem, plus activity against highly resistant enterobacteriaceae. Im ip e n e m , m e ro p e n e m , d o r ip e n e m. A n a e ro b e s.
