BIOL 3096 Chapter Notes -Titin, Motility, Myosin Light-Chain Kinase
3 Mar 2014
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Document Summary
Muscle: muscle is still composed of cells, but they are highly specialized cell, there are two types of muscle, striated and smooth muscle. It has an elaborate membrane system: electrical signals are quickly transferred to the muscle fibers. Smooth muscle: wrapped around intestines, blood vessels, and uterus. Responsible for peristalsis: reacts slowly, disorganized structure, no visible structure of membranes, though the organelles are present. In the two muscle types, there is a difference in how the myosin/actin interact. In striated muscle, myosin binding to actin is regulated by the position of tropomyosin. In turn, mlck is activated via its interaction with calmodulin. Just like troponin c must be bound to ca2+ to facilitate the shifting of tropomyocin in striated muscle, calmodulin must be bound to ca2+ in order to interact with mlck. In smooth muscle, ca2+ is stored in the smooth er, as there is not a significant sr.
