PSY 358 Chapter Notes - Chapter 13: Solitary Nucleus, Extracellular Fluid, Adrenal Medulla

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Review: pkmzeta inhibition abolishes long-term retention of spatial information, pkmzeta plays a role in the maintenance of a memory trace, pkmzeta can also enhance already established memories because when you enhance. This chapter: emotional experiences are memorable; this chapter discusses why this is the case, central idea: arousing events activate neural and hormonal processes that modulate the cellular-molecular process that consolidate memory. **diagram**-slide 23: the amygdala is connected to many regions of the brain that are likely storage sites for different types of memories. Avoidance training causes the release of norepinephrine in the amygdala: the level of norepinephrine (ne) released into the extracellular fluid in avoidance training is determined by the intensity of the shock, ie- stronger training = more ne. Norepinephrine enhances memories: the injection of ne into the amygdala enhanced memory, blocking binding of ne to its receptor with propranolol disrupted memory in the water maze, the same treatments have similar effects on avoidance learning.

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