PSYCH 212 Chapter Notes - Chapter 4: Endorphins, Dynorphin, Antipsychotic

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Neurotransmitters and neuropharmacology exogenous substance - from outside the body endogenous - from inside the body. Electrical signals are turned into chemical signals at synapses exocytosis - a cellular process that results in the release of a substance into the extracellular space. Amino acid neurotransmitters and peptide neurotransmitters are based on single amino acid molecules or short chains of amino acids. Amine neurotransmitters are based on modi cations of single amino acid nucleus (ex: acetycholine, serotonin, and dopamine) gas neurotransmitter. The most abundant excitatory and inhibitory neurotransmitters are amino acids glutamate gamma-aminobutyric (gaba) Four amine neurotransmitters modulate brain activity: acetylcholine. Cholinergic neurons are found in nuclei within basal forebrain: dopamine. Control of mood, vision, sexual behavior, anxiety, sleep, and many other functions: norepinephrine. Participate in control at a range of behaviors. Repeated treatments can reduce the effectiveness of drugs metabolic tolerance - more ef cient at clearing the drug form the body functional tolerance - changing sensitivity to drug cross-tolerance.

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