PSY30400 Chapter Notes - Chapter 7: Anisomycin, Classical Conditioning, Posttraumatic Stress Disorder
Chapter 7: Long Term-Memory – Encoding, Retrieval, and Consolidation
• Consolidation and Retrieval- Reconsolidation:
o Memories can be UPDATED
▪ we are constantly learning new things and modifying information stored in
memory in order to deal with new circumstances
o Reconsolidation:
▪ when a memory is retrieved, it becomes fragile, as it was when it was
originally formed, and that when it is in this fragile state, it needs to be
consolidated again
o Experiment by Nadar involving a rat
▪ used classical conditioning to create a fear response in the rat of freezing
to the presentation of a tone by pairing the tone with a shock
▪ Rat is injected with anisomycin when it received a tone-shock pairing so that
it cannot move
• if it is injected before consolidation occurs, then it ELIMINATES
memory, but it has no effect if injected after
• Behaves as if it never received the initial tone-shock pairing when
injection occurs before consolidation
• However, crucial condition occurs when the tone-shock occurs and
the rat freezes and then the drug is injected so the memory is
REACTIVATED and it now has an effect
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