BIOL 4177 Chapter : Ch 11 Vision

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15 Mar 2019
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Accommodation ciliary constrict, zonule relax, lens relax to ball: pigment epithelium, rods/cones (photoreceptors, outer plexiform layer, interneurons (bipolar cells, inner plexiform layer, ganglion cells. Fovea high acuity vision high density of photoreceptors. Acuity - ability to resolve two points in space. Retinal pigment epithelium (rpe: photoreceptive - absorb, disk removal - assemble at bottom, push old up, vesicle, retinoid cycle. Opsin 7tmp"s, gpcr: disks flat vesicles for sa, photon capture and transduction, house keeping mitochondrion, signal transduction. Cis-trans isomerization - 11-cis-retinal to all-trans retinal. Rhodopsin type of opsin, meta rhodopsin ii activated. Shuttles cis to rhodopsin and trans to pe. Phosphodiesterase regulate level of cyclic nucleotide. Cyclic nucleotide gated channel (cng) nonspecific cation channel (ca, na, k) On rod, k leak channels always open, cng open in dark (depol) Retina can fx over 10 log units of light intensity (10-10billion)

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