BIOL 1201 Chapter : Chapter 45 Outline 1

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15 Mar 2019
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Hormones reach everywhere, but only target cells have receptors and respond. Endocrine system = hormone responses = endocrine signaling. Stand alone hypothalamus, pineal, pituitary = in the brain thyroid, parathyroid = in the neck adrenal = above the kidneys pancreas ovaries/testes. Diffuse out, bloodstream with transporter proteins, diffuse in. Liver cells, gpcr, adenylyl cyclase, camp, pka, getting glucose from glycogen. Steroids, thyroid hormones, vitamin d metabolite (estradiol, testosterone) Coordination of endocrine and neuroendocrine systems in butterfly development. Feedback regulation, anatagonism = methods of balance = hormone pathways. Brain secretes: ptth (prothoracicotropic hormone), and juvenile hormone. Insulin = decreases blood glucose (beta cells, pancreatic islets) Endocrine pathway: stomach acid duodenum ph decrease secretion of secretin pancreas bicarbonate release ph increase. Neuroendocrine pathway: senory input (suckling) neurosecretory cell stimulus. Neurohormone (oxytocin) breat cells milk release sensory input. Diabetes mellitus = an endocrine disorder = elevated blood glucose levels. Glucagon = increases blood glucose (alpha cells, pancreatic islets)

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