BIOL 1201 Chapter : Chapter 17 OutlinePart2
Document Summary
Rna protein mrna helped by trna and translated on the rrna of the ribosome transfer rna. 80 bases, clover leaf, then folded in 3d (mostly via h-bonds) anti-codon loop. Large subunit has a, p, and e sites and the exit tunnel aminoacyl trna binding site peptidyl trna binding site exit site (for the trna) Initiation mrna + small subunit initiation factors = helper proteins the first trna starts in the p site, all others start in the a site. Gtp is the energy source for the ribosome: large subunit assembly, 2) protein chain elongationm 3) trna release. A-site binds a release factor instead of another trna+amino acid the ribosome subunits and mrna come apart. Polysomes = many ribosomes on the same mrna. Folding and post-translational modification folding (or can occur during translation) subunit assembly of multi-subunit proteins post-translational modification. Free and bound ribosomes because of their location they will translated different types of proteins bound membrane proteins free soluble proteins.
