ANSC 2133 Chapter : Ansc 2133 2 7 12
2-7-12 ANSC 2133
Growth of cell size=hypertrophy
Increase number of cells= hyperplasia
THESE SLIDES ARE NOT ON MOODLE YET
Adipocyte differentiation
1. Peroxisome proliferator-activated receptor gamma (PPARy)
2. The CCAAT/ enhancer binding protein
3. ?
Origin and Location of Bone cells
• Osteroblast cells are the ones responsible for growth
• Osteoclast are the ones that do repairs on the bone
Ossification
• Diaphysis- increasing diameter (in the middles of the bone)
• When talking about bone growth on the end we are talking about osteoblast(convert cartilage
into bone and take in calcium
• Ossification center doesn’t come in till adult reaches mature size
• Once we get to a postnatal satge the epiphyseal growth plate starts to convert the carliage into
bone after that stage happens only thing that happens to bone in u maintain it or lose it
• Osteoporosis-losing bone(hard to reverse, very serious, allows bone shafts to become weak and
it fractures)
Growth plate organization
• Prolferative zone is where we have hyperplasia growth
Intramembranous of ossification
• Ossification= strengthening
Oppositional bone growth
• As the bone progress requires more blood vessels for ossification, the bone continues to have
increase number of cells
• Osteocytes-structure site of bone
• Blood vessels continue to be replaced
Bone resorption osteoclast
Document Summary
These slides are not on moodle yet . Adipocyte differentiation: peroxisome proliferator-activated receptor gamma (ppary, the ccaat/ enhancer binding protein. Origin and location of bone cells: osteroblast cells are the ones responsible for growth, osteoclast are the ones that do repairs on the bone. Growth plate organization: prolferative zone is where we have hyperplasia growth. Oppositional bone growth: as the bone progress requires more blood vessels for ossification, the bone continues to have increase number of cells, osteocytes-structure site of bone, blood vessels continue to be replaced. Bone resorption osteoclast: once we start active bone growth its there is breakdown in growth that occurs in different parts of the cell, enzymes will break down the bone enzymes like trap and cathepsin k. Tropocallagen formation: fiberblast cells are hard to see under microscope, don"t know eactly. Collagen and tropocallgen structures: tropocallgen helixes from together to from the collagen fibril(a striated pattern)
