NRS 220 Chapter 31: adrenal gland disorders
28 Jan 2019
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Adrenal gland is most active between 7-8 am administer corticosteroids at this time hyper-secretion of adrenocorticotropic hormone (acth) > cushing syndrome. When adrenals receive pituitary signals in form of acth, responds by producing cortisol. Primary adrenal insu ciency (addisons disease): low cortisol low aldosterone. Adrenal cortex: mineralocorticoid: aldosterone: pulls in water sodium excretes potassium. Aldosterone: plays a role in bp regulation acts on kidneys to increase or decrease sodium reabsorption decreased aldosterone = sodium and potassium abnormalities. Addison"s disease = primary adrenocortical insu ciency (low of cortisol and adolesterone) The three adrenal corticosteroids: glucocorticoids = cortisol decreases in ammatory reaction decreases wbc migration to in amed area increases fat metabolism raises serum glucose, mineralocorticoids = aldosterone > uid and electrolyte balance, androgens = sex hormones. Low glucocorticoids, mineralocorticoids, and androgens stimulated anterior pituitary to increase acth > releases melanocytes dark skin pigmentation. Tx for aldosterone de ciency = spironlactone (aldactone) (potassium sparing diuretic)
