NURS 3331 Chapter Notes - Chapter 28: Kilogram, Fentanyl, Chronic Pain
Document Summary
Pharmacology chapter 28: opioid analgesics, opioid antagonists, and nonopioid centrally acting analgesics. Opioid: any drug that has actions similar to those of morphine. Classification of drugs that act at opioid receptors. 3 categories of drugs that bind opioid receptors. Administration routes: oral, im, iv, subq, epidural, intrathecal. Tolerance: a state in which a larger dose is required to produce the same response that could formerly be produced with a smaller dose. A state in which an abstinence syndrome will occur if drug use is abruptly stopped. Buprenorphine antagonists at mu receptors agonists at kappa receptors. Physical dependence, abuse, and addiction as clinical concerns. Physical dependence: a state in which an abstinence syndrome will occur if the dependence- producing drug is abruptly withdrawn. Abuse: drug use that is inconsistent with medical or social norms. Addiction: a disease process characterized by continued use of a psychoactive substance despite physical, psychologic, or social harm.