AS.020.305 Chapter 2: Exam 2 Notes (dragged) 2

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Chapter 10: membrane transport: thermodynamics of trasport, nonmediated transport occurs through simple diffusion, mediated transport occurs through the action of specific carrier proteins. The substance diffuses in the direction that eliminates its concentration gradient, at a rate proportional to the magnitude of the gradient. The rate of diffusion of a substance also depends on its solubility in the membrane"s nonpolar core: mediated transport is classified into two categories depending on the thermodynamics of the system, 1. Passive-mediated transport, or facilitated diffusion, in which a specific molecule flows from high concentration to low concentration: 2. Active transport, in which a specific molecule is transported from low concentration to high concentration, that is, against its concentration gradient. Such an endergonic process must be coupled to a sufficiently exergonic process to make it favorable (i. e. , g < 0).

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