BIOL 2344 Chapter Notes - Chapter 23: In Situ Hybridization, Hybridization Probe, Cytogenetics

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A goal of cytogenetic mapping is to determine the location of a gene on an intact. In situ hybridization localizes genes along particular chromosomes. In situ hybridization ~ technique used to cytologically map locations of genes or other. Linkage mapping can use molecular markers: molecular marker ~ segment of dna that is found at specific site along chromosome and has properties that enable it to be uniquely recognized using molecular tools, such as. Pcr and gel electrophoresis: polymorphic ~ term used to describe trait or gene (or other segment of dna) that is found in two or more forms in population. 23. 4 physical mapping via cloning and dna sequencing. Physical map of chromosome is constructed by creating contiguous series of clones that span. Chromosome: contig ~ series of clones that contain contiguous, overlapping pieces of chromosomal. Researchers can make genetic maps of large eukaryotic chromosomes.

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