BIOL 222 Chapter 9.2: Nucleic Acid Structure

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3d structure = when the double helix bends, coils, and folds for a more compact structure. Nucleotides: three components: a pentose sugar, a nitrogenous base, and at least one phosphate group. Two kinds of sugar: deoxyribose (in dna) and ribose (in rna) Five kinds of nitrogenous bases and two types: purines (adenine & guanine) and pyrimidines (thymine, cytosine, and uracil: purine = double-ring, 9 carbons pyrimidine = single-ring, 6 carbons. Bases are always attached to the 1" carbon of the sugar, and phosphate is always attached to the 5" carbon: oh group attached to the 3" carbon allows for covalent linkages between nucleotides. Nucleoside = when a base (a, t, etc. ) is attached to only sugar: there is a system of naming things found pg 230-1, ex. adenosine, adenosine monophosphate, etc. Nucleotide linkage aka phosphodiester linkage: they link in a linear fashion covalently.

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