BIOL 142 Chapter Notes - Chapter 16: Genetic Screen, Arginine, Citrulline
13 Mar 2018
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Document Summary
Dna is a double-helical structure containing sequences of four bases. Gene expression: the entire set of processes, including transcription and translation, that convert information in dna into a product of a gene, most commonly a protein. Null/loss-of-function alleles: a mutant allele that does not produce a functional product. One-gene, one-enzyme hypothesis: the hypothesis that each gene is responsible for making one enzyme. Hypothesis has expanded to include genes that produce proteins other than enzymes or that produce rnas as final products. Radiation can damage dna often makes it nonfunctional. Published on the ability of n. crassa to synthesis the amino acid arginine. Previous work showed that arginine is synthesized in a metabolic pathway. Metabolic pathway: a linked series of biochemical reactions that sequentially changes an initial substrate to form a final product; the product of one reaction is the substrate of the next reaction.
