BIOSC-116 Chapter Notes - Chapter 1: Multi-Drug-Resistant Tuberculosis, Multiple Drug Resistance, Rifampicin
9 Dec 2020
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Clinical and radiographic features of primary and reactivation pulmonary tuberculosis. mks1b, 1d (i"ve already talked about all of this. If you see anything on imaging, it"s going to be a lower or middle lung lesion or hilar/mediastinal adenopathy. If you see anything, apical posterior infiltrates - often with cavitation. there is a need for multiple drug therapy of active tuberculosis. Now, it"s better, but there are a lot of resistant strains of tb. We don"t want to breed more resistant strains so we use multiple drugs for a long time to make sure we kill it good. The key drug throughout all of these is rifampin. Isoniazid for 9 months or rifampin for 4 months or both once a week for 2 months (we have to watch you take meds) Standard is 4 drugs (ripe) for 2 months and then 2 drugs for 4 months (ri)
