BIOMG 1350 Chapter Notes - Chapter 7: Hydrolysis, Phosphodiester Bond, Base Pair

• School: Cornell University
• Department: Molecular Biology and Genetics
• Course: BIOMG 1350
• Professor: Huffaker

Document Summary

Portions of dna sequence are transcribed into dna: transcription. Copy the nucleotide sequence of a gene into rna: rna. Stretches of nucleotides can base pair with complementary sequences found elsewhere. Transcription produces rna that is complementary to one strand of dna: opening and unwinding small portion of helix to expose bases, one strand acts as template strand (other is coding strand) Incoming ribonucleotide covalently linked to growing rna chain by rna. Rna transcript looks like coding strand: rna polymerase. Catalyze formation of phosphodiester bonds that link nucleotides. Form sugar phosphate backbone of rna chain. Unwinds dna helix just ahead for pairing as it moves along: energy needed to drive rxn=atp, ctp, utp, gtp, immediate release of rna strand from dna. Many rna copies can be made in short time/at the same time: rna can start chain without a primer + not permanent info storage=mistakes.