GEN-3000 Chapter Notes - Chapter 18: Contig, Genome Size, Human Genome Project
Document Summary
Genomics field of genetics that attempts to understand the content, organization, function, and evolution of genetic information contained in whole genomes. Structural genomics studies the organization and sequence of genetic information contained within a genome. Physical maps based on the direct dna sequence. Bioinformatics emerging field consisting of molecular biology and computer science that centers on developing databases, computer-search algorithms, gene-prediction software, and other analytical tools. The goal of human genome project was to a complete copy of the human genome in 15 years. They didn"t know where to start or what approach to take. First create detailed genetic and physical maps of the genome, which provide known locations of genetic markers at regularly spaced intervals along each chromosome. They put markers along the chromosome to orient themselves of where they are along the chromosome. Come up with a general map of the genome. In the shotgun approach maps are not needed.
