SOCI 3630 Chapter Notes - Chapter 1.0: Loading Dose, Warfarin, Anticoagulant
4 Jun 2020
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Want shortest possible duration that is effective reduced risk of bleeding. Secondary unprovoked with higher bleeding risk 3 months. Key point: 3 months minimum duration of therapy for most of these key groups. Provoked/unprovoked vte provoked by a transient risk factor (provoked . In the chess guidelines 5 primary risk groups for vte recurrence there is a cause), non-transient risk factors (long travel >6 hours, drug therapies such as oral contraceptives, bedridden/immobility, trauma) Genetic disorder may cause recurrence 3 months should have a reassessment (very high risk of bleeding don"t even bother stop it) Patient should have regular re-evaluation (bleeding risk) to see whether it"s safe to continue anticoagulant therapy. Second unprovoked vte event: extended anticoagulant therapy unless high risk of bleeding and reassessment. Active cancer: use lmwh and the need to continue therapy beyond 3-6 months should be reassessed and can be influenced by other factors unique to the disease state (active cancer, metastases, chemotherapy (increased risk of vte))
