KINE 2011 Chapter Notes - Chapter 9.7: Rh Disease, Blood Transfusion, Abo Blood Group System

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Blood group system is one of the 35 known human blood groups systems. Rh +/- refers to presense of d antigen. D antigen is used to determine risk of hemolytic disease of newborn for rh disease management. An individual either has rh factor (d-antigen) on surface of rbc or doesn t. Immunization against rh can occur through blood transfusion or placental exposure during pregnancy in women. It will be treated as a foreign invader and your body will produce antibodies against it. But it can cause problems if you become pregnant again with another rhesus-positive baby. The antibodies that your body made in your first pregnancy can quickly multiply, cross the placenta and attack the blood cells of your baby. will be stronger than the first pregnancy and can cause rhesus disease in your baby. Your antibodies start to attack your baby"s blood cells during pregnancy and can carry on attacking them for a few months after the birth.

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