KINE 2011 Chapter Notes - Chapter 1.4: Active Transport, Dephosphorylation, Phosphorylation
29 Oct 2017
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Establish na+ & k+ gradient across membrane. Gradients important in ability of nerve & muscle cells to generate electric signals. Energy used by pump indirectly serves as energy source for co- transport of glucose & aa cross intestinal & kidney cells. Secondary active transport: intestinal & kidney cells actively transport glucose & aa by moving them up concentration gradient, intestinal cells transport nutrients from inside lumen to blood. It used second-hand energy stored in form of ion concentration gradient to co-transport: in case of kidney & intestine, glucose concentration is higher inside cells. Affinity of binding site of facilitative diffusion is same on both sides of membrane. Pumps: with at, binding site has greater affinity for molecule on low-concentration side due to phosphorylation of carrier on this side. Carrier exhibits atpase activity in that it splits terminal phosphate from atp molecule.
