BIOL 2060 Chapter Notes - Chapter 13.2: Pyuria, Nephron, Esterase
20 Apr 2018
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Summary of kidney & regulation of blood pressure. Manage fluid balance in ecf & icf. Ecf must be isotonic with cells: direct effect of map & gfr- high map, high gfr low water retention. Low map, low bf, low pgc, low gfr: sns lowers gfr through vasoconstriction. Low pgp, decrease net fileration, less gfr reabsorption > filteration . No constriction, up bf, high pgc, up net filteration, up gfr fiteration> reabsorption. Vasoconstriction increase tpr, increase map by increase fluid retention: hormonal effect. Vasopressin: collecting permeable by inserting water channels in lumen. Released stimulated by osmoreceptors in hypotha (increase osmolarity) & left atrial volume receptors (low volume in atria) . Renin (kidney): released when low nacl, atria bp, ecf. Secreted by juxtaglomerular cells when low plasma volume by sns stimulation of intrarenal baroreceptors. Aldosterone: acts on kidney to increase na+ reab in ascending. Indirect cl- & water . enters plasma, in tubular initiates mrna transcription of new channels (na+, k+,na+/k+.
