BIOL 2021 Chapter Notes - Chapter 2.3: Cancer Stem Cell, Adult Stem Cell, Bone Marrow
2 Apr 2018
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Stem cells: not terminally differentiated, can divide without limit, creation of 2 daughter cells after division, daughters can either differentiate or can remain a stem cell, self-renewal: remains a stem cells after division. Hemopoietic stem cells for making blood cells: found in bone marrow. There are stem cells in almost all tissues. Stem cells are rare and divide very slowly, so they are difficult to locate. In transit from being a stem cell to a differentiated cell. Differentiated cells can be continually replaced but a few stem cells always remain. Advantages: division rate can increase rapidly when more cells are required, reduces the chances of mutations in stem cells because they have few divisions and divide slowly (prevents cancer) Cancer most often arises in self-renewing tissues (cells that divide fast: epidermis, thelium, bone marrow. Cancer stem cells are few in number, divide slowly, and divide indefinitely.
