PS268 Chapter Notes - Chapter 16: Dihydrotestosterone, Plasma Cell, Skeletal Muscle
Document Summary
In 50s, drug companies began to synthesize various steroids that have fewer androgenic effects and more anabolic effects than testosterone (called anabolic steroids) though none are entirely free of androgenic effects. In healthy men who engage in weight training and maintain proper diet, anabolic steroids produce small increases in lean muscle mass and muscular strength. However no evidence for an overall increase in aerobic capacity or endurance. Stacking: taking more than one steroid at a time, ex both an oral and injectable form. Users report they feel they can lift more or work harder when on steroids; may be due to. Cns effects like stimulant-like feeling of energy and loss of fatigue, or increased aggressiveness leading to more aggressive training, or an active placebo effect. Anabolic-androgenic steroids are drugs that mimic effects of endogenous hormones testosterone and dihydrotestosterone. Anabolic steroids are fat soluble hormones thus can penetrate plasma cell membranes.
